Magnetic bead separation technology has gained a series of remarkable research results in molecular biology, cytology, immunology and biochemistry since early 1970s. The targets to be separated can be efficiently enriched by utilizing the combination between surface modified magnetic particles and biomolecule or cell.
Magnetic bead is a kind of microsphere carrier with certain magnetism and structure which fabricated by the combination of superparamagnetic particles and organic polymer. The outermost layer of magnetic bead is the functional group which can exhibit different physical properties according to the type of functional group (e.g. –OH, -COOH, -CHO, -NH2, -SH, -CONO2, -CONH2) include Hydrophobic-Hydrophilic, polar-nonpolar and positive chargre-negative charge, therefore, magnetic bead can combine with different ligands base on above physical properties, such as anti-body, antigen, DNA and RNA. Magnetic bead also show magnetic response under the external magnetic field.
Neodymium Magnets for Magnetic Bead Separation Rack
Magnetic bead separation system consists of three parts: the magnetic bead, test tube and magnetic bead separation rack. Neodymium magnets will provide the strong enough magnetic field to magnetize superparamagnetic nanoparticles, and thus magnetic bead can be quickly secured. It should be noted that neodymium magnets for magnetic bead separation risk should have superior dimensional, appearance and magnetic performance consistency.
